Back in one of my early games, I had run out of all food except for plants, and I was constantly brewing. Then I noticed my dwarves dying left and right.
I really can’t think of a more appropriate way for a fortress to fail then by the dwarves brewing literally every edible thing into alcohol and subsequently starving to death.

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Too bad you didn’t know to cook the booze into even more delicious deep fried booze… the ultimate cure for sobriety.
They died partying noble lads…